HER2/neu (654-662) GP2

发表于由

HER2/neu (654-662) GP2;

HER2/neu (654-662) GP2 是一种由 9 个氨基酸残基组成的多肽，来源于人类表皮生长因子受体 2 HER2/nue (654-662)，可诱导 HLA-A2 限制性细胞毒性 T 淋巴细胞 (CTL) 对多种上皮肿瘤发生反应。

HER2/neu (654-662) GP2amp;;

HER2/neu (654-662) GP2 Chemical Structure

CAS No. : 160790-21-6

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生物活性

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].

分子量

884.11

Formula

C42H77N9O11
CAS 号

160790-21-6
Sequence

Ile-Ile-Ser-Ala-Val-Val-Gly-Ile-Leu
Sequence Shortening

IISAVVGIL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306.

    [2]. Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4.