Angiotensin I/II (1-6)

Angiotensin I/II (1-6);

Angiotensin I/II 1-6 含有 1-6 个氨基酸,由血管紧张素 I/II 肽转化而来。Angiotensin I 被血管紧张素转换酶 (ACE)水解形成具有生物活性的 angiotensin II。Angiotensin II 用于高血压、肾素-血管紧张素系统和特发性膜性肾病的研究。

Angiotensin I/II (1-6)amp;;

Angiotensin I/II (1-6) Chemical Structure

CAS No. : 47896-63-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
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Angiotensin I/II (1-6) 的其他形式现货产品:

Angiotensin I/II (1-6) (TFA)

生物活性

Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

体外研究
(In Vitro)

Angiotensin II is a naturally occurring octapeptide hormone component of the renin-angiotensin-aldosterone system (RAAS) and is a potent vasoconstrictor. Angiotensin II has important roles in cardiovascular, neurologic, and renal physiology, including maintenance of blood pressure, thirst sensation, response to the baroreceptor reflex, determination of renal blood flow and glomerular filtration rate, and electrolyte and free water homeostasis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

801.89

Formula

C36H55N11O10

CAS 号

47896-63-9

Sequence Shortening

DRVYIH

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Erdös EG, et al. Conversion of angiotensin I to angiotensin II. Am J Med. 1976 May 31;60(6):749-59.

    [2]. Busse LW, et al. Clinical Experience With IV Angiotensin II Administration: A Systematic Review of Safety. Crit Care Med. 2017;45(8):1285-1294.

    [3]. Angiotensin II