GAD65 (206-220)

GAD65 (206-220);

GAD65 (206-220) 来源于谷氨酸脱羧酶 (GAD) 65 蛋白的 180-188 残基。GAD65 与 I-Ag7 的 MHC II 类分子结合呈递给 T 细胞,也是在 I 型糖尿病中被自身反应性 T 细胞靶向的主要胰腺抗原。

GAD65 (206-220)amp;;

GAD65 (206-220) Chemical Structure

CAS No. : 245124-26-9

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生物活性

GAD65 (206-220) is glutamic acid decarboxylase (GAD) 65-derived peptide, corresponding to residues 180-188. GAD65 is presented to T cells in association with I-Ag7 MHC class II molecules and a major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus[1].

分子量

1757.03

Formula

C86H129N15O24

CAS 号

245124-26-9

Sequence Shortening

TYEIAPVFVLLEYVT

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Seon-Kyeong Kim, et al. Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells. Proc Natl Acad Sci U S A