GR-73632

发表于2023年11月13日由Whatman官网

GR-73632;

GR-73632 是新型速激肽神经激肽1 (NK-1) 受体激动剂。 GR-73632 通过传递瘙痒信号的 NK1 受体直接作用于初级感觉神经元的外周末端。

GR-73632amp;;

GR-73632 Chemical Structure

CAS No. : 133156-06-6

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性	GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist^[1]. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals^[2].
IC₅₀ Target	IC50: NK-1 receptor^[1]
分子量	766.00
Formula	C₄₀H₅₉N₇O₆S
CAS 号	133156-06-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Sakurada C, et al. Spinal actions of GR73632, a novel tachykinin NK1 receptor agonist. Peptides. 1999;20(2):301-4. [2]. Costantini VJ, et al. The NK1 receptor antagonist aprepitant attenuates NK1 agonist-induced scratching behaviour in the gerbil after intra-dermal, topical or oral administration. Exp Dermatol. 2015 Apr;24(4):312-4.