P-113

P-113;

P-113 是一种源自人类唾液蛋白组蛋白 5 的抗菌肽 (AMP)。P-113 对临床上重要的微生物(如假单胞菌属、葡萄球菌属和白色念珠菌)具有活性。

P-113amp;;

P-113 Chemical Structure

CAS No. : 190673-58-6

规格 价格 是否有货 数量
1 mg ¥800 In-stock
5 mg ¥2300 In-stock
10 mg ¥3500 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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P-113 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans[1].

体外研究
(In Vitro)

P-113 has a minimum inhibitory concentration (MIC) value of 3.13 µg/mL for against C. albicans[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1563.81

Formula

C71H110N28O13

CAS 号

190673-58-6

Sequence Shortening

AKRHHGYKRKFH-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 100 mg/mL (63.95 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6395 mL 3.1973 mL 6.3946 mL
5 mM 0.1279 mL 0.6395 mL 1.2789 mL
10 mM 0.0639 mL 0.3197 mL 0.6395 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Kuang-Ting Cheng, et al. The Interactions between the Antimicrobial Peptide P-113 and Living Candida albicans Cells Shed Light on Mechanisms of Antifungal Activity and Resistance. Int J Mol Sci. 2020 Apr 10;21(7):2654.

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