Calmodulin-Dependent Protein Kinase II(290-309) acetate; 纯度: 98.97%
Calmodulin-Dependent Protein Kinase II (290-309) acetate 是有效的 CaMK 拮抗剂, 抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的 IC50 值为52 nM。
Calmodulin-Dependent Protein Kinase II(290-309) acetate Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥2400 | In-stock | |
5 mg | ¥6500 | In-stock | |
10 mg | ; | 询价 | ; |
50 mg | ; | 询价 | ; |
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Calmodulin-Dependent Protein Kinase II(290-309) acetate 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1]. |
IC50 Target |
IC50: 52 nM (calmodulin-dependent protein kinase II)[1]. |
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体外研究 (In Vitro) |
Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
2333.88 |
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Formula |
C105H189N31O26S |
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Sequence Shortening |
LKKFNARRKLKGAILTTMLA |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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参考文献 |
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