HAEGTFTSDVS

HAEGTFTSDVS; 纯度: 98.31%

HAEGTFTSDVS是GLP-1多肽N-端的1-11残基。

HAEGTFTSDVSamp;;

HAEGTFTSDVS Chemical Structure

CAS No. : 864915-61-7

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1 mg ¥1600 In-stock
5 mg ¥5000 In-stock
10 mg ¥8000 In-stock
50 mg ; 询价 ;
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HAEGTFTSDVS 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.

体外研究
(In Vitro)

The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1150.18

Formula

C48H71N13O20

CAS 号

864915-61-7

Sequence

His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser

Sequence Shortening

HAEGTFTSDVS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

参考文献
  • [1]. US20120264685

    [2]. US9738697