HAEGT

发表于由

HAEGT; 纯度: 99.26%

HAEGT 是胰高血糖素样肽-1 (GLP-1) 的多肽 N-端的 1-5 残基片段。HAEGT 可作为竞争性底物，检测人二肽基肽-IV (DPP-IV) 的底物结合位点。

HAEGTamp;;

HAEGT Chemical Structure

CAS No. : 852155-81-8

规格 价格 是否有货 数量
1 mg ￥1600 In-stock
5 mg ￥4800 In-stock
10 mg ￥6800 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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HAEGT 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptidomimetic Library
  • Peptide Library

生物活性

HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide. HAEGT can acts as competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV[1].

分子量

513.50

Formula

C20H31N7O9
CAS 号

852155-81-8
Sequence

His-Ala-Glu-Gly-Thr
Sequence Shortening

HAEGT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Lisa M. Kopcho, et al. Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach. Archives of Biochemistry and Biophysics 436 (2005) 367–376.