Arg-Gly-Asp-Cys TFA

Arg-Gly-Asp-Cys TFA;

Arg-Gly-Asp-Cys TFA 是纤维粘连蛋白与细胞粘附分子的结合基序,能够抑制血小板凝集以及纤维蛋白原结合。

Arg-Gly-Asp-Cys TFAamp;;

Arg-Gly-Asp-Cys TFA Chemical Structure

CAS No. : 2171504-22-4

规格 价格 是否有货 数量
5 mg ¥770 In-stock
10 mg ¥1250 In-stock
25 mg ¥2500 In-stock
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Arg-Gly-Asp-Cys TFA 相关产品

bull;相关化合物库:

  • Covalent Screening Library Plus
  • Bioactive Compound Library Plus
  • Covalent Screening Library
  • Anti-Cardiovascular Disease Compound Library
  • Peptide Library

生物活性

Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding[1].

体外研究
(In Vitro)

Arg-Gly-Asp-Cys-functionalized chitosan (0.25-1 mg/mL; 2-7 days) favors cell growth and an increase in cellular proliferation compared to the control cells (viability >140%)[1].
Arg-Gly-Asp-Cys-functionalizes chitosan derivatives exhibit in vitro wound healing properties by enhancing fibroblast proliferation and adhesion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

563.51

Formula

C17H28F3N7O9S

CAS 号

2171504-22-4

Sequence Shortening

RGDC

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light, stored under nitrogen

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro:;

H2O : 250 mg/mL (443.65 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7746 mL 8.8730 mL 17.7459 mL
5 mM 0.3549 mL 1.7746 mL 3.5492 mL
10 mM 0.1775 mL 0.8873 mL 1.7746 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Patrulea V, et, al. Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing. Carbohydr Polym. 2016 May 20;142:114-23.