Gluten Exorphin C

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Gluten Exorphin C; 纯度: 98.97%

Gluten exorphin C 是一种源自谷朊粉的阿片肽。在 GPI 和 MVD 检测中，抑制 μ opioid 和 δ opioid 活性，IC50 值分别为 40 μM 和13.5 μM。

Gluten Exorphin Camp;;

Gluten Exorphin C Chemical Structure

CAS No. : 142479-62-7

规格 价格 是否有货 数量
1 mg ￥1100 In-stock
5 mg ￥1900 In-stock
10 mg ￥2900 In-stock
25 mg ￥5900 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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生物活性

Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

IC50 Target

IC50: 40 μM (μ opioid), 13.5 μM (δ opioid)[1]
体外研究
(In Vitro)

Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

591.70

Formula

C29H45N5O8
CAS 号

142479-62-7
Sequence

Tyr-Pro-Ile-Ser-Leu
Sequence Shortening

YPISL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 100 mg/mL (169.00 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6900 mL 8.4502 mL 16.9005 mL
5 mM 0.3380 mL 1.6900 mL 3.3801 mL
10 mM 0.1690 mL 0.8450 mL 1.6900 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Fukudome S, et al. Gluten exorphin C. A novel opioid peptide derived from wheat gluten. FEBS Lett. 1993 Jan 18;316(1):17-9.