β-Amyloid (1-15)(Synonyms: Amyloid β-Protein (1-15))

发表于由

β-Amyloid (1-15);(Synonyms: Amyloid β-Protein (1-15)) 纯度: 96.63%

β-Amyloid (1-15) 是β-淀粉样蛋白片段。 β-淀粉样蛋白是在阿尔茨海默病患者的脑中形成淀粉样斑块的肽。

β-Amyloid (1-15)amp;;(Synonyms: Amyloid β-Protein (1-15))

β-Amyloid (1-15) Chemical Structure

CAS No. : 183745-81-5

规格 价格 是否有货 数量
1 mg ￥770 In-stock
5 mg ￥2100 In-stock
10 mg ￥3300 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

beta;-Amyloid (1-15) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Neuronal Signaling Compound Library
  • Anti-Alzheimer’s Disease Compound Library
  • Neurodegenerative Disease-related Compound Library
  • Peptide Library

生物活性

β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer’s disease (AD) patients.

IC50 Target

Amyloid-β[1]
体外研究
(In Vitro)

β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. [1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1826.84

Formula

C78H107N25O27
CAS 号

183745-81-5
Sequence Shortening

DAEFRHDSGYEVHHQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (27.37 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.5474 mL 2.7370 mL 5.4739 mL
5 mM 0.1095 mL 0.5474 mL 1.0948 mL
10 mM 0.0547 mL 0.2737 mL 0.5474 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Portelius E, et al. Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer’s disease. J Alzheimers Dis. 2012;31(2):335-41.