GRGDSP

GRGDSP;

GRGDSP 是一种合成的线性RGD肽,是一种整联蛋白 (integrin) 抑制剂。

GRGDSPamp;;

GRGDSP Chemical Structure

CAS No. : 91037-75-1

规格 价格 是否有货
5 mg ¥1600 询问价格 货期
10 mg ¥2900 询问价格 货期
25 mg ¥6400 询问价格 货期

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GRGDSP 的其他形式现货产品:

GRGDSP TFA

生物活性

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

IC50 Target

Integrin[1]

体外研究
(In Vitro)

It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

587.58

Formula

C22H37N9O10

CAS 号

91037-75-1

Sequence

Gly-Arg-Gly-Asp-Ser-Pro

Sequence Shortening

GRGDSP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Qian J, et al. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol. 2016 Jun 7;22(21):5042-9.

    [2]. Patel S, et al. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J Biomed Mater Res A. 2007 Nov;83(2):423-33.