LGnRH-III, lamprey

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LGnRH-III, lamprey; 纯度: 98.76%

LGnRH-III, lamprey，从七鳃鳗中分离出的一种 GnRH 亚型，是一种具有抗肿瘤活性的弱 GnRH 激动剂。

LGnRH-III, lampreyamp;;

LGnRH-III, lamprey Chemical Structure

CAS No. : 147859-97-0

规格 价格 是否有货 数量
1 mg ￥1200 In-stock
5 mg ￥3000 In-stock
10 mg ￥4800 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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LGnRH-III, lamprey 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Cancer Compound Library
  • Peptide Library

生物活性

LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities[1][2].

IC50 Target

GnRH[2]
分子量

1259.33

Formula

C59H74N18O14
CAS 号

147859-97-0
Sequence

{pGLP}-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2
Sequence Shortening

{pGLP}-HWSHDWKPG-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (39.70 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.7941 mL 3.9704 mL 7.9407 mL
5 mM 0.1588 mL 0.7941 mL 1.5881 mL
10 mM 0.0794 mL 0.3970 mL 0.7941 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98(6):525-34.

    [2]. Manea M, et al. lGnRH-III — a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20(4):439-49.