Syntide 2

发表于由

Syntide 2;

Syntide 2 是一种 Ca2+– 和钙调蛋白 (CaM) 依赖性蛋白激酶 II (CaMKII) 底物肽，选择性地抑制赤霉素 (GA) 反应，使组成和脱落酸调节事件不受影响。

Syntide 2amp;;

Syntide 2 Chemical Structure

CAS No. : 108334-68-5

规格 价格 是否有货
1 mg ￥850 询问价格 货期
5 mg ￥3000 询问价格 货期
10 mg ￥5000 询问价格 货期

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Syntide 2 的其他形式现货产品:

Syntide 2 TFA

生物活性

Syntide 2, a Ca2+– and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected[1].

IC50 Target

Ca2+

;

CaMKII

;

分子量

1507.82

Formula

C68H122N20O18
CAS 号

108334-68-5
Sequence

Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys
Sequence Shortening

PLARTLSVAGLPGKK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Ritchie S, et al. Calcium-Dependent Protein Phosphorylation May Mediate the Gibberellic Acid Response in Barley Aleurone. Plant Physiol. 1998 Feb 1;116(2):765-76.