MART-1 (26-35) (human) TFA

发表于由

MART-1 (26-35) (human) TFA; 纯度: 98.19%

MART-1 (26-35) (human) TFA 是 MART-1 蛋白 26 至 35 氨基酸片段。

MART-1 (26-35) (human) TFAamp;;

MART-1 (26-35) (human) TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ￥900 In-stock
5 mg ￥3600 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

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MART-1 (26-35) (human) TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

MART-1 (26-35) (human) TFA is amino acid residue 26 to 35 of MART-1 protein.

体外研究
(In Vitro)

MART-1 (Melan-A) gene is 18 kb long and comprises five exons. It is expressed in most melanoma tumor samples, and among normal cells, only in melanocytes [1] . In cancer immunotherapy, epitopes and variants derived from the MART-1/Melan-A protein are widely used as clinical vaccines. The epitopes spanning amino acid residues 26–35 and 27–35 from the MART-1/Melan-A protein, highly expressed in melanoma cells, provide a prime example of T cell recognition of multiple peptides and the use of peptide variants designed to elicit altered immunological responses [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1057.12

Formula

C44H75F3N10O16
Sequence

Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val
Sequence Shortening

EAAGIGILTV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 5 mg/mL (4.73 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.9460 mL 4.7298 mL 9.4597 mL
5 mM — — —
10 mM — — —

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Coulie PG, et al. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med. 1994 Jul 1;180(1):35-42.

    [2]. Borbulevych OY, et al. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36.