Dynorphin A (1-8)

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Dynorphin A (1-8); 纯度: 99.07%

Dynorphin A (1-8) 是胎盘组织提取物中主要的阿片肽。Dynorphin A (1-8) 是 kappa 受体最可能的天然配体。Dynorphin A (1-8) 抑制 3H-Bremazocine 与纯化的 kappa 受体的结合 (IC50=303 nM)。

Dynorphin A (1-8)amp;;

Dynorphin A (1-8) Chemical Structure

CAS No. : 75790-53-3

规格 价格 是否有货 数量
5 mg ￥1500 In-stock
10 mg ￥2400 In-stock
25 mg ￥5000 In-stock
50 mg ￥8200 In-stock
100 mg ; 询价 ;
200 mg ; 询价 ;

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Dynorphin A (1-8) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
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  • Peptide Library

生物活性

Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].

分子量

981.15

Formula

C46H72N14O10
CAS 号

75790-53-3
Sequence

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile
Sequence Shortening

YGGFLRRI
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Stored under nitrogen

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (stored under nitrogen)
溶解性数据
In Vitro:;

H2O : 100 mg/mL (101.92 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.0192 mL 5.0961 mL 10.1921 mL
5 mM 0.2038 mL 1.0192 mL 2.0384 mL
10 mM 0.1019 mL 0.5096 mL 1.0192 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Agbas A, Ahmed MS, Millington W, et al. Dynorphin A(1-8) in human placenta: amino acid sequence determined by tandem mass spectrometry. Peptides. 1995;16(4):623-627.

    [2]. Ahmed MS, Zhou DH, Cavinato AG, Maulik D. Opioid binding properties of the purified kappa receptor from human placenta. Life Sci. 1989;44(13):861-871.