Cyclosporin A-Derivative 1 Free base; 纯度: 99.29%
Cyclosporin A-Derivative 1 (Free base) 是环孢菌素 A 衍生的结晶中间体，来自专利 WO 2013167703 A1。Cyclosporin A 是一种免疫抑制剂，能够与亲环蛋白结合并抑制钙调磷酸酶。
Cyclosporin A-Derivative 1 Free base Chemical Structure
CAS No. : 286852-20-8
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥1500 | In-stock | |
| 5 mg | ￥3500 | In-stock | |
| 10 mg | ; | 询价 | ; |
| 50 mg | ; | 询价 | ; |
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Cyclosporin A-Derivative 1 Free base 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
| 生物活性 |
Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin. |
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| 体外研究 (In Vitro) |
Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporin A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1276.69 |
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| Formula |
C65H117N11O14 |
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| CAS 号 |
286852-20-8 |
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| Sequence |
Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar} |
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| Sequence Shortening |
LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar} |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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