Luteinizing hormone (human)(Synonyms: 黄体生成素 (人))

发表于由

Luteinizing hormone (human);(Synonyms: 黄体生成素 (人))

Luteinizing hormone (human) 是垂体 (LH) 产生的一种异二聚体糖蛋白激素，在人类生殖中起关键作用。

Luteinizing hormone (human)amp;;(Synonyms: 黄体生成素 (人))

Luteinizing hormone (human) Chemical Structure

CAS No. : 39341-83-8

规格 价格 是否有货
10 μg ￥7350 询问价格 货期

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生物活性

Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction[1].

IC50 Target

LHR[1]
体外研究
(In Vitro)

Luteinizing hormone (human) binds to luteinizing hormone receptor (LHR) in human and non-human species which are mainly expressed in the ovary and testis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 号

39341-83-8
中文名称

黄体生成素 (人)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Laura Riccetti, et al. Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors. Sci Rep. 2017 Apr 19;7(1):940.