TAT-Gap19 TFA; 纯度: 98.36%
TAT-Gap19 TFA 是一种 Cx 模拟肽,是一种特定的 connexin43 半通道 (Cx43 HC) 抑制剂。TAT-Gap19 TFA 不抑制相应的 Cx43 GJC。TAT-Gap19 TFA 可以透过血脑屏障,减轻小鼠的肝纤维化。
TAT-Gap19 TFA Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥2200 | In-stock | |
10 mg | ¥3700 | In-stock | |
50 mg | ; | 询价 | ; |
100 mg | ; | 询价 | ; |
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TAT-Gap19 TFA 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
TAT-Gap19 TFA, a Cx mimetic peptide, is a specific connexin43 hemichannel (Cx43 HC) inhibitor. TAT-Gap19 TFA does not inhibits the corresponding Cx43 GJCs. TAT-Gap19 TFA traverses the blood-brain barrier and alleviate liver fibrosis in mice[1][2][3]. |
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体内研究 (In Vivo) |
A single injection of TAT-Gap19 TFA (i.v. via the tail vein; 55 mg/kg) produces significant immune signal in the brain 24 h later in 4 months old C57Bl6 male mice[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
2817.27 |
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Formula |
C121H213F3N46O28 |
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Sequence Shortening |
YGRKKRRQRRRKQIEIKKFK |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
H2O : 100 mg/mL (35.50 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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