Dynorphin B (1-13) (TFA)(Synonyms: 强啡肽 B (1-13) 三氟乙酸盐)

发表于由

Dynorphin B (1-13) (TFA);(Synonyms: 强啡肽 B (1-13) 三氟乙酸盐) 纯度: 99.52%

Dynorphin B (1-13) TFA 是一种阿片样 κ 受体 (κ-opioid receptor) 激动剂。

Dynorphin B (1-13) (TFA)amp;;(Synonyms: 强啡肽 B (1-13) 三氟乙酸盐)

Dynorphin B (1-13) (TFA) Chemical Structure

规格 价格 是否有货 数量
1 mg ￥1650 In-stock
5 mg ￥6600 In-stock
10 mg ￥9900 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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Dynorphin B (1-13) (TFA) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor.

IC50 Target

κ-opioid receptor[1]
体外研究
(In Vitro)

Dynorphin B (1-13), a 13 amino acid, is an extraordinarily potent opioid peptide. The neurophysiological actions of Dynorphin B (1-13) have been the subject of considerable research effort[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1684.86

Formula

C76H116N21F3O19
Sequence

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr
Sequence Shortening

YGGFLRRQFKVVT
中文名称

强啡肽 B (1-13) 三氟乙酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Chavkin C. Dynorphin–still an extraordinarily potent opioid peptide. Mol Pharmacol. 2013 Apr;83(4):729-36.