Fibronectin; 纯度: ge;96.0%
Fibronectin 是存在于血液和细胞中的糖蛋白(~500 kDa)，是组织损伤的生物标记物。Fibronectin 可与整合素结合。Fibronectin 还与其它细胞外基质蛋白如胶原蛋白、纤维蛋白和硫酸肝素蛋白聚糖结合。
Fibronectin Chemical Structure
CAS No. : 86088-83-7
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Fibronectin, a glycoprotein (~500 kDa) present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans.
Fibronectin (FN) is a glycoprotein present in blood as well as in cells. While Fibronectin (FN) in blood has many functions, its primary role is to promote wound repair following injury. Increases in plasma Fibronectin (FN) has been reported after inflammation, trauma, and diseases such as atherosclerosis. Tobacco-related lung diseases are characterized by increased accumulation of Fibronectin (FN) which can be induced by nicotine. We found significant increases of plasma Fibronectin (FN) following exposure to e-cig aerosols and TS. Although our study examined the levels of 8-oxodG, CRP, and Fibronectin (FN), additional markers for lung injury need be explored in future studies.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Room temperature in continental US; may vary elsewhere.
Protect from light
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
H2O : 8.33 mg/mL (ultrasonic and adjust pH to 7 with NaOH)