Janelia Fluor® 646, Azide(Synonyms: JF646, Azide)

Janelia Fluor® 646, Azide;(Synonyms: JF646, Azide)

Janelia Fluor® 646, Azide (JF646, Azide) 是一种红色荧光染料,含有 click chemistry 基团叠氮化物。Janelia Fluor® 646, Azide 可用于活细胞成像实验中。Janelia Fluor® 产品在美国专利下获得许可,来自 Howard Hughes Medical Institute 的 No.9,933,417,10,018,624,10,161,932 和其他专利。

Janelia Fluor® 646, Azideamp;;(Synonyms: JF646, Azide)

Janelia Fluor® 646, Azide Chemical Structure

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生物活性

Janelia Fluor® 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor® 646, Azide can be used for live-cell imaging experiments[1][2]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

Maximum absorption wavelength (λabs)= 646 nm, maximum emission wavelength (λem)=664 nm[1].
JF646 can serve as a ligand for self-labeling tag (such as HaloTag)[1].
Janelia Fluor® 646, Azide is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

696.87

Formula

C37H44N6O6Si

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Grimm JB, Muthusamy AK, Liang Y, et al. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nat Methods. 2017;14(10):987-994. doi:10.1038/nmeth.4403.

    [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.