Janelia Fluor® 585, SE(Synonyms: JF585, SE JF585, NHS)

发表于由

Janelia Fluor® 585, SE;(Synonyms: JF585, SE; JF585, NHS)

Janelia Fluor® 585, SE (JF585, SE) 是一种橙色荧光染料，含有 NHS 酯，能与伯胺基共轭。Janelia Fluor® 585, SE 可用于结构光照明 (SIM) 和受激发射损耗荧光显微技术(STED)，还可转化为光活化衍生物用于单分子定位显微镜 (SMLM) 实验。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 585, SEamp;;(Synonyms: JF585, SE; JF585, NHS)

Janelia Fluor® 585, SE Chemical Structure

CAS No. : 1811539-88-4

规格 是否有货
1 mg 询价

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生物活性

Janelia Fluor® 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor® 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

Maximum absorption wavelength (λabs)=585 nm, maximum emission wavelength (λem)=609 nm[1].
The JF585-SNAP-tag ligand (24) also functioned as a cellular label. The new HaloTag ligands derived from JF585 and JF635 show a high degree of chromogenicity and fluorogenicity, a critical parameter in advanced imaging experiments[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

649.59

Formula

C34H27F4N3O6
CAS 号

1811539-88-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Grimm JB, Muthusamy AK, Liang Y, et al. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nat Methods. 2017;14(10):987-994. doi:10.1038/nmeth.4403