HBC599

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HBC599;

HBC599 是一种非荧光 HBC 模拟物。HBC 在溶液中是非荧光的，但在与 Pepper RNA 适体形成紧密的络合物时会发出强烈的荧光。HBC-Pepper 复合物可用于观察活细胞中 RNA 的动态变化。

HBC599amp;;

HBC599 Chemical Structure

CAS No. : 2530162-00-4

规格 价格 是否有货
5 mg ￥2000 询问价格 货期
10 mg ￥3500 询问价格 货期
25 mg ￥7000 询问价格 货期
50 mg ￥11000 询问价格 货期

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生物活性

HBC599 is a HBC analog. HBC is nonfluorescent in solution, but emits strong fluorescence upon forming tight complex with Pepper RNA aptamer. HBC-Pepper complex can be used to visualize RNA dynamics in live cells[1].

体外研究
(In Vitro)

Pepper can activate the fluorescence of HBC. Mammalian cells expressing Pepper exhibits robust greenyellowish fluorescence on incubation with 1 μM HBC[1].
Peppers allow simple and robust imaging of diverse RNA species in live cells with minimal perturbation of the target RNA’s transcription, localization and translation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

359.44

Formula

C21H17N3OS
CAS 号

2530162-00-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Chen X, et al. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol. 2019 Nov;37(11):1287-1293.