K114;
K114,一种刚果红染料类似物,与淀粉样纤维 (amyloid fibrils) 紧密结合,其 EC50 值为 20-30 nM。K114 是一种高效的精液源性病毒感染增强剂 (SEVI) 检测剂。
K114 Chemical Structure
CAS No. : 872201-12-2
规格 | 价格 | 是否有货 | |
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2 mg | ¥1100 | 询问价格 货期 | |
5 mg | ¥2200 | 询问价格 货期 |
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生物活性 |
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM[1]. K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI)[2]. |
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体外研究 (In Vitro) |
K114’s unusually low buffer fluorescence is due to self-quenching in sedimentable aggregates or micelles which upon interacting with amyloid fibrils undergo an enhancement in fluorescence intensity and shifts in the excitation and emission spectra[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
393.27 |
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Formula |
C22H17BrO2 |
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CAS 号 |
872201-12-2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:;
DMSO : 100 mg/mL (254.28 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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