荧光染料FM-red(Synonyms: PSH-red)

发表于由

荧光染料Dye Reagents FM-red;(Synonyms: PSH-red)

FM-red (PSH-red) 是一种发红光且对环境敏感的探针，用于选择性检测和标记蛋白硫醇。FM-red 可用于在活细胞和体内蛋白质巯基的成像。 FM-red 也可用于测量硫氧还蛋白 (Trx) 的氧化还原状态。

FM-red(Synonyms: PSH-red)

FM-red Chemical Structure

规格 价格 是否有货
5 mg ￥3500 询问价格 货期
10 mg ￥5800 询问价格 货期

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生物活性

FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx)[1].

体外研究
(In Vitro)

FM-red (10 μM; 30 min) is suitable for imaging protein thiols in HeLa cells[1].
FM-red (20 μM; 48 h) has no significant cytotoxicity in HeLa cells[1].
FM-red possesses a long emission wavelength (~655 nm) and fast response (~10 min) by binding to protein thiols[1].
FM-red exhibits time- and concentration-dependent fluorescence response to bovine serum albumin (BSA)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

FM-red (10 μM; 30 min) could be used to image protein thiols in zebrafishes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

788.29

Formula

C41H46ClN5O9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hu G, et, al. Depletion of protein thiols and the accumulation of oxidized thioredoxin in Parkinsonism disclosed by a red-emitting and environment-sensitive probe. J Mater Chem B. 2019 Apr 28;7(16):2696-2702.