荧光染料Janelia Fluor® 646, Maleimide(Synonyms: JF646, Maleimide)

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荧光染料Dye Reagents Janelia Fluor® 646, Maleimide;(Synonyms: JF646, Maleimide)

Janelia Fluor® 646, Maleimide (JF646, Maleimide) 是一种含有马来酰亚胺修饰基团的红色荧光染料。JF646, Maleimide 可用于细胞成像研究。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 646, Maleimide(Synonyms: JF646, Maleimide)

Janelia Fluor® 646, Maleimide Chemical Structure

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生物活性

Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging[1][2]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

λmax (nm)=646; λem (nm)=664[1].
JF646 can serve as a ligand for self-labeling tag (such as HaloTag)[1].
JF646, Maleimide is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

618.75

Formula

C35H34N4O5Si
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Grimm JB, et al. A general method to improve fluorophores for live-cell and single-molecule microscopy. Nat Methods. 2015;12(3):244-250. doi:10.1038/nmeth.3256

    [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.