生化分析试剂 Biochemical Assay Reagents
Ethoxylated hydrogenated castor oil;(Synonyms: PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated)
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) 是聚乙二醇 (PEG) 与天然蓖麻油的混合物。Ethoxylated hydrogenated castor oil 可用于水包油 (o/w) 乳浊液的乳化和增溶。Ethoxylated hydrogenated castor oil 可以作为动物实验的助溶剂。
Ethoxylated hydrogenated castor oil Chemical Structure
CAS No. : 61788-85-0
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 500 mg | ￥500 | In-stock | |
| 1 g | ; | 询价 | ; |
| 5 g | ; | 询价 | ; |
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| 生物活性 |
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1]. |
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| 体内研究 (In Vivo) |
20% PEG-40 hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice[1].PEG-40 hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females[1].A toxicity study of blank nanoemulsion using PEG-40 hydrogenated castor oil as a surfactant is applied in order to load various active compounds for oral administration[2].Nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Clinical Trial |
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| CAS 号 |
61788-85-0 |
| 中文名称 |
聚氧乙烯氢化蓖麻油 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4deg;C, protect from light |
| 溶解性数据 |
In Vitro:;
H2O : ≥ 100 mg/mL * “≥” means soluble, but saturation unknown. |
| 参考文献 |
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