Acanthoside B

天然产物 糖类和糖苷 Saccharides and Glycosides

Acanthoside B;

Acanthoside B 是一种具有抗炎、抗遗忘活性的生物活性木脂素。Acanthoside B 可用于阿尔茨海默病和肺部炎症等疾病的研究。

Acanthoside B

Acanthoside B Chemical Structure

CAS No. : 7374-79-0

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5 mg ¥2500 In-stock
10 mg ¥3600 In-stock
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Acanthoside B 相关产品

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  • Anti-Alzheimer’s Disease Compound Library
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生物活性

Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be used for alzheimer’s disease and lung inflammation research[1]

体内研究
(In Vivo)

Acanthoside B (oral gavage; 10-20 mg/kg; 7 days prior to Scopolamine injection) attenuates Scopolamine inflicted AD-like amnesic traits by restoring the cholinergic activity, decreasing the endogenous antioxidant status, suppressing neuroinflammation, and activating the TrkB/CREB/BDNF pathway in mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Scopolamine-induced amnesic mouse model[1]
Dosage: 10 mg/kg; 20 mg/kg
Administration: oral gavage; 7 days
Result: Exhibited an anti-amnesic effect in mice.

分子量

580.58

Formula

C28H36O13

CAS 号

7374-79-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Govindarajan Karthivashan, et al. Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative/inflammatory/cholinergic systems and activation of the TrkB/CREB/BDNF pathway. Food Chem Toxicol. 2019 Jul;129:444-457.

    [2]. Ju Hee Lee, et al. Inhibition of Lung Inflammation by Acanthopanax divaricatus var. Albeofructus and Its Constituents. Biomol Ther (Seoul). 2016 Jan;24(1):67-74.