天然产物 糖类和糖苷 Saccharides and Glycosides
Niazinin 是一种硫代氨基甲酸酯糖苷，具有抗利什曼原虫活性，IC50 值为 5.25 μM。Niazinin 还显示出与目标蛋白 3CL 蛋白酶的结合亲和力。Niazinin 具有杀利什曼原虫、抗炎和解热活性。
Niazinin Chemical Structure
CAS No. : 147821-57-6
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Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity.
Niazinin, is cytotoxic at substantially higher concentration (CC50 of 31.6 µM) than its antileishmanial concentration (IC50 of 5.25 µM).
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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