Nasunin(Synonyms: Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside)

天然产物 糖类和糖苷 Saccharides and Glycosides

Nasunin;(Synonyms: Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside)

Nasunin 是一种抗氧化花青素、具有抗血管生成活性。

Nasunin(Synonyms: Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside)

Nasunin Chemical Structure

CAS No. : 28463-30-1

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity[1].

体外研究
(In Vitro)

Nasunin at higher 10 µM suppresses microvessel outgrowth in an ex vivo angiogenesis assay using a rat aortic ring[1].
Nasunin suppresses HUVEC proliferation in a dose-dependent manner (50-200 µM)[1].
Nasunin diminishes LPS-induced nuclear factor-κB (NF-κB) activation by suppressing the degradation of inhibitor of κB-α and nuclear translocation of p65 subunit of NF-κB. Nasunin also attenuates the phosphorylation of Akt and p38, signaling molecules involved in pro-inflammatory mediator production[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

955.26

Formula

C42H47ClO23

CAS 号

28463-30-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kiminori Matsubara, et al. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels. J Agric Food Chem. 2005 Aug 10;53(16):6272-5.

    [2]. Wataru Komatsu, et al. Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways. Biosci Biotechnol Biochem. 2017 Oct;81(10):1956-1966.

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