Isoastragaloside I(Synonyms: Isoastragaloside-I)

天然产物 糖类和糖苷 Saccharides and Glycosides

Isoastragaloside I;(Synonyms: Isoastragaloside-I)

异黄芪皂苷I(Isoastragaloside I)是中药黄芪的一种天然化合物,具有提高脂联素量活性。

Isoastragaloside I(Synonyms: Isoastragaloside-I)

Isoastragaloside I Chemical Structure

CAS No. : 84676-88-0

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Isoastragaloside I 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Glycoside Compound Library
  • Medicine Food Homology Compound Library
  • Terpenoids Library

生物活性

Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production. IC50 value: Target: Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex.

分子量

869.04

Formula

C45H72O16

CAS 号

84676-88-0

中文名称

异黄芪皂苷 I;异黄芪苷 I

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

参考文献
  • [1]. Xu A, et al. Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice. Endocrinology. 2009 Feb;150(2):625-33.