Salicortin(Synonyms: 特里杨甙)

天然产物 糖类和糖苷 Saccharides and Glycosides

Salicortin;(Synonyms: 特里杨甙)

Salicortin 是一种酚类糖苷,已从许多植物 (如胡杨和柳属植物) 中分离出来。Salicortin 通过下调 JNKNF-κB/NFATc1 信号通路抑制破骨细胞分化和骨吸收。Salicortin 具有抗遗忘,抗脂肪形成和免疫调节活性。

Salicortin(Synonyms: 特里杨甙)

Salicortin Chemical Structure

CAS No. : 1887055-63-1

规格 是否有货
100 μg 询价
1 mg 询价
5 mg 询价

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生物活性

Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity[1].

IC50 Target[1]

JNK

;

NF-κB

;

体外研究
(In Vitro)

Salicortin (100 μM; 2 hours) almost completely retards the phosphorylation of IκBα[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: Mouse bone marrow macrophage (BMM)
Concentration: 100 μM
Incubation Time: 2 hours
Result: Retarded the phosphorylation of IκBα.

分子量

424.40

Formula

C20H24O10

CAS 号

1887055-63-1

中文名称

特里杨甙

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nie S, et al. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Biochem Biophys Res Commun. 2016 Jan 29;470(1):61-67.