Icariside E5(Synonyms: 淫羊藿次甙E5)

天然产物 糖类和糖苷 Saccharides and Glycosides

Icariside E5;(Synonyms: 淫羊藿次甙E5) 纯度: ge;93.0%

Icariside E5 是从 Albiziae Cortex 分离得到的木脂素糖苷。Icariside E5 促进 HUVEC 的增殖而无细胞毒性。Icariside E5 具有抗氧化性能。

Icariside E5(Synonyms: 淫羊藿次甙E5)

Icariside E5 Chemical Structure

CAS No. : 126176-79-2

规格 价格 是否有货 数量
5 mg ¥18500 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Icariside E5 is a lignan glycoside isolated from the Albiziae Cortex. Icariside E5 promotes the proliferation of HUVECs without cytotoxicity. Icariside E5 has antioxidant properties[1][2].

体外研究
(In Vitro)

Icariside E5 (5, 10, 20, 40 µM; for 48 h) slightly promotes the proliferation of human umbilical vein endothelial cells (HUVECs). Icariside E5 does not have the pharmacological effect of scavenging ROS[1].
Icariside E neither induces an increase in the intracellular levels of reactive oxygen species nor affects the mitochondria permeability transition, and it does not signal through the vanilloid receptor type 1. It protects Jurkat cells from apoptosis induced by the oxidative stress mediated by serum withdrawal[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

522.54

Formula

C26H34O11

CAS 号

126176-79-2

中文名称

淫羊藿次甙E5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Xuelin Shi, et al. Chemical Constituents from Albiziae Cortex and Their Ability to Ameliorate Steatosis and Promote Proliferation and Anti-Oxidation In Vitro. Molecules. 2019 Nov 7;24(22):4041.

    [2]. M Iorizzi, et al. New glycosides from Capsicum annuum L. var. acuminatum. Isolation, structure determination, and biological activity. J Agric Food Chem. 2001 Apr;49(4):2022-9.

发表回复