天然产物 糖类和糖苷 Saccharides and Glycosides
Soyasaponin II 纯度: 99.81%
Soyasaponin II 是具有抗病毒活性的皂苷。Soyasaponin II 抑制 HSV-1,HCMV,流感病毒和 HIV-1 的复制。Soyasaponin II 对 HSV-1 复制显示出有效的抑制作用。Soyasaponin II 作为 YB-1 磷酸化和 NLRP3 炎性小体引发的抑制剂,可保护小鼠免受 LPS/GalN 诱导的急性肝衰竭。
Soyasaponin II Chemical Structure
CAS No. : 55319-36-3
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥1500 | In-stock | |
5 mg | 询价 | ||
10 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure[1][2]. |
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IC50 & Target[1][2] |
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体外研究 (In Vitro) |
Soyasaponin II inhibits the replication of HSV-1 (IC50=54μM), HCMV (104μM), influenza virus (88μM), and HIV-1 (112 μM)[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Soyasaponin II (5 mg/kg; p.o.; once a day for three consecutive days) ameliorates canonical NLRP3 inflammasome-associated innate immune response[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
913.10 |
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Formula |
C47H76O17 |
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CAS 号 |
55319-36-3 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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参考文献 |
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