天然产物 天然产物苯丙素类 Phenylpropanoids
Heraclenin (Synonyms: 独活内酯) 纯度: 99.59%
Heraclenin，是一种天然呋喃香豆素，通过靶向激活的 T 细胞核因子 (NFAT) 来抑制人原代 T 细胞中 T 细胞受体介导的增殖，这种作用存在浓度依赖性。
Heraclenin Chemical Structure
CAS No. : 2880-49-1
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥1710 | In-stock | |
| 5 mg | ￥5140 | In-stock | |
| 10 mg | 询价 | ||
| 50 mg | 询价 |
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Heraclenin 相关产品
•相关化合物库:
- Covalent Screening Library Plus
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Immunology/Inflammation Compound Library
- Natural Product Library
- Covalent Screening Library
- Traditional Chinese Medicine Monomer Library
| 生物活性 |
Heraclenin, a natural furanocoumarin, significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT)[1]. |
IC50 & Target |
NFAT[1] |
|---|---|
| 分子量 |
286.28 |
| Formula |
C16H14O5 |
| CAS 号 |
2880-49-1 |
| 中文名称 |
独活素；独活内酯 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| 参考文献 |
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