Luteolin 5-O-glucoside(Synonyms: 木犀草素-5-O-葡萄糖苷)

天然产物 黄酮类 Flavonoids

Luteolin 5-O-glucoside (Synonyms: 木犀草素-5-O-葡萄糖苷)

Luteolin 5-O-glucoside 来自 Cirsium maackii,具有抗炎活性。Luteolin 5-O-glucoside 抑制 LPS 诱导的 NO 生成和 t-BHP 诱导的 ROS 生成。Luteolin 5-O-glucoside 作用于巨噬细胞,还抑制 iNOS 和 COX-2 表达。

Luteolin 5-O-glucoside(Synonyms: 木犀草素-5-O-葡萄糖苷)

Luteolin 5-O-glucoside Chemical Structure

CAS No. : 20344-46-1

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生物活性

Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1].

体外研究
(In Vitro)

Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

448.38

Formula

C21H20O11

CAS 号

20344-46-1

中文名称

木犀草素-5-O-葡萄糖苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Anti-inflammatory activity of Korean thistle Cirsium maackii and its major flavonoid, luteolin 5-O-glucoside.Food Chem Toxicol. 2012 Jun;50(6):2171-9.