Pectolinarigenin(Synonyms: 柳穿鱼黄素)

发表于由

天然产物 黄酮类 Flavonoids

Pectolinarigenin (Synonyms: 柳穿鱼黄素) 纯度: 99.47%

Pectolinarigenin 是 COX-2/5-LOX 的双重抑制剂。具有抗炎活性。Pectolinarigenin 对黑素生成具有有效的抑制作用。

Pectolinarigenin(Synonyms: 柳穿鱼黄素)

Pectolinarigenin Chemical Structure

CAS No. : 520-12-7

规格 价格 是否有货 数量
5 mg ￥1190 In-stock
10 mg ￥2020 In-stock
20 mg ￥3430 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Pectolinarigenin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Anti-Aging Compound Library
  • Ferroptosis Compound Library
  • Phenols Library
  • Pyroptosis Compound Library
  • Traditional Chinese Medicine Monomer Library
  • Flavonoids Library
  • Anti-Pancreatic Cancer Compound Library
  • Lipid Metabolism Compound Library
  • Food-Sourced Compound Library
  • Anti-Colorectal Cancer Compound Library

生物活性

Pectolinarigenin is a dual inhibitor of COX-2/5-LOX. Anti-inflammatory activity[1]. Pectolinarigenin has potent inhibitory activities on melanogenesis[2].

IC50 & Target[1]

COX-2

 

5-LOX

 

分子量

314.29

Formula

C17H14O6
CAS 号

520-12-7
中文名称

柳穿鱼黄素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 33.33 mg/mL (106.05 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1818 mL 15.9089 mL 31.8177 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL
10 mM 0.3182 mL 1.5909 mL 3.1818 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Lim H, et al. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull. 2008 Nov;31(11):2063-7.

    [2]. Lee S, et al. Pectolinarigenin, an aglycone of pectolinarin, has more potent inhibitory activities on melanogenesis than pectolinarin.Biochem Biophys Res Commun. 2017 Nov 4;493(1):765-772.