Myrciacetin

天然产物 黄酮类 Flavonoids

Myrciacetin 

Myrciacetin 是一种黄酮类化合物。Myrciacetin 对大鼠晶状体醛糖还原酶 (aldose reductase) 有抑制作用,IC50 为 13 μM 。

Myrciacetin

Myrciacetin Chemical Structure

CAS No. : 203734-35-4

规格 是否有货
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生物活性

Myrciacetin is a flavonoid from Rhododendron dauricum. Myrciacetin is against rat lens aldose reductase with an IC50 of 13 μM[1].

IC50 & Target

IC50: aldose reductase[1]

体外研究
(In Vitro)

Aldose reductase catalizes the reduction of glucose to sorbitol in the polyol pathway and is related to chronic complications such as peripheral neuropathy, retinopathy, and cataracts[1].
Myrciacetin shows potent inhibitory activity against rat lens aldose reductase with an IC50 of 13 μM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

316.31

Formula

C17H16O6

CAS 号

203734-35-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hisashi MATSUDA,et al. Antidiabetic Principles of Natural Medicines. V.1) Aldose Reductase Inhibitors from Myrcia multiflora DC. (2): Structures of Myrciacitrins III, IV, and V. N Chem. Pharm. Bull. 50(3) 429—431 (2002)

    [2]. Xin-Wei Lou, et al. Identification and characterization of three new flavonoids from Rhododendron dauricum. Chin J Nat Med