Euphol acetate

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Euphol acetate 

Euphol acetate 是一种三萜烯类化合物,可以从 Euphorbia broteri 中提取得到。Euphol acetate 是肝转运蛋白 OATP1B1/3 的抑制剂。

Euphol acetate

Euphol acetate Chemical Structure

CAS No. : 13879-04-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3)[1][2].

IC50 & Target

OATP1B1/3[2]

体外研究
(In Vitro)

Euphol acetate (10 μM) suppresses the uptake of the OATP1B substrate sodium fluorescein in OATP1B1 (29.2%)- or 1B3 (40.2%)-transfected CHO cells[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

468.75

Formula

C32H52O2

CAS 号

13879-04-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. DePascual Teresa, et al. Triterpenes from Euphorbia broteri. Phytochemistry. 1987. 26(6): 1767-1776.

    [2]. Tom De Bruyn, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83(6):1257-67.

发表回复