20-Hydroxyganoderic Acid G(Synonyms: 20-羟基灵芝酸G)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

20-Hydroxyganoderic Acid G (Synonyms: 20-羟基灵芝酸G)

20-Hydroxyganoderic Acid G 是从灵芝 (Ganoderma curtisii) 子实体的 EtOH 提取物中获得的羊毛甾烷三萜类化合物。20-Hydroxyganoderic Acid G 抑制由 LPS 激活的 BV-2 小胶质细胞,IC50 为 21.33 μM。20-Hydroxyganoderic Acid G 用于 LPS 激活的小胶质细胞相关的神经炎症疾病的研究。

20-Hydroxyganoderic Acid G(Synonyms: 20-羟基灵芝酸G)

20-Hydroxyganoderic Acid G Chemical Structure

CAS No. : 400604-12-8

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生物活性

20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the drug discovery of nerve inflammation diseases associated with microglia activated by LPS[1].

分子量

548.66

Formula

C30H44O9

CAS 号

400604-12-8

中文名称

20-羟基灵芝酸G

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61.