Paederosidic acid methyl ester(Synonyms: 紫草酸甲酯)

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Paederosidic acid methyl ester (Synonyms: 紫草酸甲酯)

Paederosidic acid methyl ester 是一种 ATP 敏感的 K+ channel 通道激活剂,从 P. scandens 中分离。 Paederosidic acid methyl ester 表现出显着的中枢缓解疼痛活性,通过激活脑中和脊髓水平中 ATP 敏感型 K+ 通道提高了痛觉阈值。

Paederosidic acid methyl ester(Synonyms: 紫草酸甲酯)

Paederosidic acid methyl ester Chemical Structure

CAS No. : 122413-01-8

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生物活性

Paederosidic acid methyl ester is a ATP‐sensitive K+ channel activator, isolated from P. scandens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating ATP‐sensitive K+ channel in the brain and spinal cord level[1].

IC50 & Target

IC50: K+ channel[1]

分子量

478.47

Formula

C19H26O12S

CAS 号

122413-01-8

中文名称

紫草酸甲酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chen YF,et al.Possible mechanism involved in the antinociceptive activity of dimer of paederosidic acid and paederosidic acid methyl ester in mice.CNS Neurosci Ther. 2014 Feb;20(2):188-90.