Spathulenol

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Spathulenol  纯度: ≥95.0%

Spathulenol 分离自 Psidium guineense Sw,具有抗氧化,抗炎,抗增殖和抗分枝杆菌活性。 Spathulenol 在 DPPH 系统中显示出高抗氧化活性,IC50 为 85.60 μg/mL。

Spathulenol

Spathulenol Chemical Structure

CAS No. : 6750-60-3

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1 mg ¥3430 In-stock
5 mg ¥10290 In-stock
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Spathulenol 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].

体外研究
(In Vitro)

Spathulenol exhibits a high antioxidant activity s in the DPPH and MDA system, exhibits significant DPPH free radical activity, with IC50 values of 85.60 μg/mL[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Spathulenol (oral administration; 300 mg/kg) shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model[1].
In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature and oxygenation conditions, PG-1 exhibits a high activity with an IC50 value of 26.13 μg/mL, respectively, which is comparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA, which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

220.35

Formula

C15H24O

CAS 号

6750-60-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Nascimento KF, et al. Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol.J Ethnopharmacol. 2018 Jan 10;210:351-358.