上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Saikogenin A (Synonyms: 柴胡皂苷元A) 纯度: 98.31%
Saikogenin A 可从中药柴胡中提取,是一种二肽基肽酶 IV (DPP-IV) 抑制剂。
Saikogenin A Chemical Structure
CAS No. : 5092-09-1
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥7500 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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生物活性 |
Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor. |
IC50 & Target |
DPP-IV[1] |
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体外研究 (In Vitro) |
Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
472.70 |
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Formula |
C30H48O4 |
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CAS 号 |
5092-09-1 |
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中文名称 |
柴胡皂苷元A |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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参考文献 |
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