Ganoderic acid Y(Synonyms: 灵芝酸Y)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Ganoderic acid Y (Synonyms: 灵芝酸Y) 纯度: 99.07%

Ganoderic acid Y 是一种 α-葡萄糖苷酶 (α-glucosidase) 抑制剂,对酵母 α-葡萄糖苷酶的 IC50 为170 μM。Ganoderic acid Y 通过阻止肠道病毒 71 (EV71) 的脱膜而抑制其复制。

Ganoderic acid Y(Synonyms: 灵芝酸Y)

Ganoderic acid Y Chemical Structure

CAS No. : 86377-52-8

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生物活性

Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating[1][2].

体外研究
(In Vitro)

Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

454.68

Formula

C30H46O3

CAS 号

86377-52-8

中文名称

灵芝酸Y

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Chen XQ, et al. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. Phytochemistry. 2018 May;149:103-115.

    [2]. Zhang W, et al. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12.