LL-37, human TFA

发表于由

LL-37, human TFA; 纯度: 99.71%

LL-37, human TFA 是一种具有 37 个残基的两亲性组织蛋白酶衍生的抗菌肽，具有广泛的抗菌活性。LL-37, human TFA 有助于保护角膜免受感染，调节伤口愈合。

LL-37, human TFAamp;;

LL-37, human TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ￥1250 In-stock
5 mg ￥2600 询价
10 mg ; 询价 ;
50 mg ; 询价 ;

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LL-37, human TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Infection Compound Library
  • Antibacterial Compound Library
  • Peptide Library

生物活性

LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity[1]. LL-37, human TFA could help protect the cornea from infection and modulates wound healing[2].

分子量

4607.28

Formula

C205H340N60O53.C2HF3O2
Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
Sequence Shortening

LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 100 mg/mL (21.70 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.2170 mL 1.0852 mL 2.1705 mL
5 mM 0.0434 mL 0.2170 mL 0.4341 mL
10 mM 0.0217 mL 0.1085 mL 0.2170 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Dürr UH, et al. LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta. 2006 Sep;1758(9):1408-25.

    [2]. Huang LC, et al. Multifunctional roles of human cathelicidin (LL-37) at the ocular surface. Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2369-80.