S961 acetate; 纯度: 99.52%
S961 acetate 是一种高亲和力的胰岛素受体 (insulin receptor, IR) 拮抗剂,对 HIR-A,HIR-B 和人胰岛素样生长因子 I 受体 (HIGF-IR) 的 IC50 分别为 0.048,0.027 和 630 nM。
S961 acetate Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥3000 | In-stock | |
10 mg | ; | 询价 | ; |
50 mg | ; | 询价 | ; |
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S961 acetate 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1]. |
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体外研究 (In Vitro) |
S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
4864.18 |
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Formula |
C213H301N55O72S2 |
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Sequence Shortening |
GSLDESFYDWFERQLGGGSGGSSLEEEWAQIQCEVWGRGCPSY (Disulfide bridge: Cys33-Cys40) |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
H2O : 1.79 mg/mL (0.37 mM; ultrasonic and adjust pH to 8 with NaOH) |
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参考文献 |
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