Apelin-13 TFA

Apelin-13 TFA; 纯度: 97.75%

Apelin-13 是 APJ 受体的内源性配体,激活G蛋白偶联受体的 EC 50 值为 0.37 nM。

Apelin-13 TFAamp;;

Apelin-13 TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ¥550 In-stock
5 mg ¥1650 In-stock
10 mg ¥2800 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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Apelin-13 TFA 相关产品

bull;相关化合物库:

  • Clinical Compound Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM.

Clinical Trial

分子量

1664.85

Formula

C71H112F3N23O18S

Sequence

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Sequence Shortening

QRPRLSHKGPMPF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 100 mg/mL (60.07 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6007 mL 3.0033 mL 6.0065 mL
5 mM 0.1201 mL 0.6007 mL 1.2013 mL
10 mM 0.0601 mL 0.3003 mL 0.6007 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Tatemoto, K., Hosoya, M., Habata, Y., et al. Isolation and characterizaton of a novel endogenous peptide ligand for the human APJ receptor. Biochemical and Biophysical Research Communications 251, 471-476 (1998).

    [2]. Li M,et al. Apelin 13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high fat diet. Mol Med Rep. 2018 Dec;18(6):5784-5790.