Insulin(cattle)(Synonyms: 牛胰岛素 Insulin from bovine pancreas)

发表于由

Insulin(cattle);(Synonyms: 牛胰岛素; Insulin from bovine pancreas) 纯度: ge;98.0%

Insulin cattle (Insulin from bovine pancreas) 是在胰腺 β 细胞中产生的两链多肽激素。Insulin cattle 在很多哺乳动物细胞培养体系中用作生长因子。

Insulin(cattle)amp;;(Synonyms: 牛胰岛素; Insulin from bovine pancreas)

Insulin(cattle) Chemical Structure

CAS No. : 11070-73-8

规格 价格 是否有货 数量
10 mg ￥600 In-stock
25 mg ￥1100 In-stock
50 mg ￥1600 In-stock
100 mg ￥2700 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

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Insulin(cattle) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells.

体外研究
(In Vitro)

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 μg/mL of medium.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

5733.49

Formula

C254H377N65O75S6
CAS 号

11070-73-8
Sequence

Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala. Gly-Ile-Val-Glu-Gln-Cys-Cys-Ala-Ser-Val-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn (Disulfide bridge: Cys7-Cys7′, Cys19-Cys20′, Cys6′
Sequence Shortening

FVNQHLCGSHLVEALYLVCGERGFFYTPKA. GIVEQCCASVCSLYQLENYCN (Disulfide bridge: Cys7-Cys7′, Cys19-Cys20′, Cys6′-Cys11′)
中文名称

牛胰岛素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 11 mg/mL (1.92 mM; ultrasonic and adjust pH to 2 with HCl)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.1744 mL 0.8721 mL 1.7441 mL
5 mM — — —
10 mM — — —

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Yousefi R, et al. Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreaticinsulin. J Biomol Struct Dyn. 2016;34(2):362-75.