NT 13(Synonyms: TPPT)

NT 13;(Synonyms: TPPT)

NT 13 (TPPT) 是具有氨基酸序列L-苏氨酰-L-脯氨酰-L-脯氨酰-L-苏氨酰胺的四肽。 NT 13可用于抑郁症,焦虑症和其他相关疾病的研究。

NT 13amp;;(Synonyms: TPPT)

NT 13 Chemical Structure

CAS No. : 117928-93-5

规格 价格 是否有货
1 mg ¥5500 询问价格 货期
5 mg ¥22000 询问价格 货期

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生物活性

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

IC50 Target

Target: NMDAR[1]

体外研究
(In Vitro)

NT 13 derivatives are used in the study of depression, anxiety, and other related diseases. Some NT 13 derivatives are NMDAR partial agonist[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

414.45

Formula

C18H30N4O7

CAS 号

117928-93-5

Sequence

Thr-Pro-Pro-Thr

Sequence Shortening

TPPT

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
In Vitro:;

DMSO : ≥ 122.5 mg/mL (295.57 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4128 mL 12.0642 mL 24.1284 mL
5 mM 0.4826 mL 2.4128 mL 4.8257 mL
10 mM 0.2413 mL 1.2064 mL 2.4128 mL

参考文献
  • [1]. Moskal J. Methods of treating depression and other related diseases. US9340576B2